Genomic Characterization of Bladder Cancer Cell Lines using CGH Arrays. Homo sapiens

Genomic rearrangements involving different chromosome translocation in bladder cancer cell lines and in primary tumor samples Overall design: DNA extracted from 3 Bladder Cancer Cell lines (SW1710, JON, RT-4), and 1 bladder cancer (372C) in T3 Tumor stage and Grade 3 primary sample, were processed, Cy5 labeled and hybridized on Agilent CGH Arrays. As control DNA we used Cy3 labeled probes prepared starting from a pool of female DNA obtained mixing the DNA extracted from 20 healthy donors.