Results of alignment of T and B-cell epitopes with M2 and NP consensus sequences, challenge viruses and influenza viruses obtained from humans before 2014 with hemagglutinin type H1, H2, H3 and neuraminidase type N1 and N2, and from human H5N1 viruses.

Epitopes that are completely contained in NP and M2 of challenge viruses and epitope-enriched sequences are marked with color filling. B and T-cell epitopes that occur in the indicated viruses are marked with yellow and orange colors, respectively; B-cell epitopes that occur in all viruses, except for swine ones, are marked with light-blue; B-cell epitopes that occur in all viruses, but are of human origin, are marked with light-green; T-cell epitopes, that occur in all viruses, except for the viruses of human origin, are marked with red; T-cell epitopes that occur in viruses originating from birds are marked with the dark-green color; T-cell epitopes that occur in all viruses, but are of human origin, are marked with purple; B-cell epitopes that occur in human H1N1 and swine virus are marked with magenta.
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