Downregulation of γ-crystallin protein and mRNA in adult αA-CLEF lenses.
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https://figshare.com/articles/dataset/_Downregulation_of_947_crystallin_protein_and_mRNA_in_adult_945_A_CLEF_lenses_/838103
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(A, C) Western blot analysis shows less γ-crystallin in total (A) and soluble (C) protein extract of adult αA-CLEF lenses compared to wild-type. (B, D) Quantification of band density of total (B) and soluble (D) lens protein extract western blot analysis. (E) Quantitative RT-PCR expression analysis of γ-crystallins in adult wild-type and αA-CLEF lenses. mRNA expression of γA-, γC-, γD- and γEF-crystallin is significantly lower in adult αA-CLEF lenses. (F) Quantitative RT-PCR expression analysis of γ-crystallins in E16.5 wild-type and αA-CLEF lenses. mRNA expression of γA-, γB-, γC-, γD- and γEF-crystallin is significantly lower already in E16.5 αA-CLEF lenses (**p<0.01).
创建时间：
2016-02-23
