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PVT1 lincRNA signals an androgen-dependet transcriptional activation program of oncogenes in prostate cancer cells

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Zenodo2025-09-19 更新2026-05-26 收录
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The results of signals obtained with CUT&RUN for histone marks (H3K4me1, H3K4me3, H3K27ac and H3K27me3), EZH2 and AR occupancy along the human genome are available here. Briefly, prostate cancer LNCaP cells were treated with androgen analog R1881 or with solvent (EtOH), with or without PVT1 knockdown. The names of the files describe the type of histone mark or protein studied, if there is PVT1 knockdown (sg134) or not (ntc), and treatment with R1881 or EtOH. For instance, the file AR_sg134_R1881_r1.bw corresponds to the bigWig file of a CUT&RUN assay with anti-AR antibody in cells with PVT1 knockdown treated with androgen analog (R1881) and replicate 1.

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2025-09-19
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