Expression data from human fetal and adult neutrophils

Fetal neutrophils from early embryonic stages display a reduced capacity to react to inflammatory stimuli, therefore this study aimed to investigate the underlying molecular mechanisms regulating fetal neutrophil function during ontogeny. Whole transcriptome analysis of human fetal cord blood-derived neutrophils from premature (<37 weeks of gestation) and mature (>37 weeks of gestation) infants, compairing their gene expression profiles to neutrophils from healthy adult donors Human fetal and adult neutrophils were purified, RNA was isolated and loaded on a Hgu133plus (Affymetrix, Santa Clara, CA).