Spotting disease artificially infected Strongylocentrotus intermedius Raw sequence reads. Strongylocentrotus intermedius

sea urchins were artificially infected using Vibrio sp. to obtain spotting diseased and undiseased samples. We constructed nine transcriptome libraries from coelomocytes of diseased, undiseased, and control S. intermedius. RNA-seq was subsequently performed using an Illumina Hiseq 4000 platform to examine the differences in immune-related gene expression. We aimed to clarify the signal transduction pathways involved in immune defense against the infection of the causative bacterium of spotting disease at transcriptome level. This process might help us understand sea urchin antibacterial immunity and could be valuable for developing disease control strategy in aquaculture and in the selective breeding of sea urchins.