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Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells.

ChEBI2012-08-27 更新2026-07-21 收录

癌症表观遗传学

细胞重编程

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35913 数据链接链接失效反馈

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Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells.

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创建时间：

2012-08-27

癌症表观遗传学

药物耐药性

Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic

DataONE2020-06-24 更新60

C2C12 murine myoblast cell line and 48 h 10 uM BIO treated C2C12 cellulate. Mus musculus

细胞重编程

心肌细胞去分化机制

In urodele amphibians, limb regeneration involves the dedifferentiation of muscle myotubes into single cells that may acquire pluripotent potential. We have employed small molecules (myoseverin and BI

NIAID Data Ecosystem50

Additional file 5 of Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming

细胞重编程

维生素C生化作用

Additional file 5: Table S4. Reagents and resources used in the current studies.

NIAID Data Ecosystem40

Direct reprogramming of mouse fibroblasts into functional skeletal muscle progenitors. Mus musculus

细胞重编程

骨骼肌细胞

Skeletal muscle harbors quiescent stem cells termed satellite cells and proliferative progenitors termed myoblasts, which play pivotal roles during muscle regeneration. However, current technology doe

NIAID Data Ecosystem50

Comparison of hiPSCs, hESCs and fibroblasts

细胞重编程

基因表达谱比较分析

In our study, PRDM14 and NFRkB were found to enhance the reprogramming of human fibroblasts to hiPSCs in the presence of OCT4, SOX2, KLF4, with/without c-MYC (OSK/OSKC). To examnie if the obtained hiP

NIAID Data Ecosystem50

Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells.

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