Crystal Structure of the human MLKL pseudokinase domain bound to compound 2
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Crystal Structure of the human MLKL pseudokinase domain bound to compound 2 Descriptor: 1,2-ETHANEDIOL, 1-[2-fluoranyl-5-(trifluoromethyl)phenyl]-3-[4-[methyl-[2-[(3-sulfamoylphenyl)amino]pyrimidin-4-yl]amino]phenyl]urea, Mixed lineage kinase domain-like protein Authors: Cowan, A.D, Murphy, J.M, Pierotti, C.L, Lessene, G.L, Czabotar, P.E. Deposit date: 2019-03-04 Release date: 2020-09-16 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.285 Å) Cite: Potent Inhibition of Necroptosis by Simultaneously Targeting Multiple Effectors of the Pathway. Acs Chem.Biol., 15, 2020
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2019-03-04
