Mapping of low-salt soluble chromatin identifies known and novel transcriptionally active genes in chicken erythrocytes. Mapping of low-salt soluble chromatin identifies known and novel transcriptionally active genes in chicken erythrocytes

Transcriptional regulation is regulated by the organization of the genome into chromatin compartments and domains. Here, we present the detailed characteristics, including location of nucleosome-free regions, of several novel transcriptionally active/poised chromatin compartments exhibiting a range of transcriptional activities. These chromatin patterns illustrate how the salt solubility profile of a genomic region aids in the annotation of genes expressed in erythroid cells and contributes to the identification of functional features such as regulatory regions. Overall design: Examination of open chromatin regions in Chicken Immature erythrocyte cells.