Mitochondrial bioenergetic efficiency and capacity in A. aegypti females flight muscle using different substrates.

Values of bioenergetic efficiency (slope) were expressed as mean ± SD of OXPHOS versus maximum uncoupled respiratory rate linear regression and correlation analyses made in S7 Fig. Correlation coefficient values (Spearman or Pearson) were depicted as superscript letters “a” or “b”, respectively. P values represent the statistical significance of linear regression slopes in each group. Bioenergetic capacity (OXPHOS) values represent the respiratory rates data induced by ADP and calculated by subtracting the ADP rates by their equivalent "leak" values shown in Table 3 (for isolated mitochondria) and Table 4 (for flight muscle). Statistical analyses on bioenergetic capacity in isolated mitochondria were performed by using Mann Whitney test (indicated by superscript astersiks) as well as ANOVA and a posteriori Tukey´s test (indicated by superscript symbols) for flight muscle. Significant differences in isolated mitochondria were* p.005 relative to G3P and PC+Mal, and** p.0001 relative to PC+Mal. In flight muscle, significant difference was#p.001 relative to G3P.Mitochondrial bioenergetic efficiency and capacity in A. aegypti females flight muscle using different substrates.