5-methylcytosine modifition of mRNA from hippocampi in young and aged mice

To investigate the Epigenetics changes during aging, we sequenced hippocampal tissue from young and old mice by methylated RNA immunoprecipitation sequencing (MeRIP-seq) We then performed 5-methylcytosine profiling analysis using data obtained from mRNA MeRIP-seq of young and aged hippocampus tissues. Overall design: Comparative 5-methylcytosine profiling analysis of MeRIP-seq data for young and aged hippocampus tissues.