Selected model input parameters for the base-case analysis (See S1 Table for complete list and ranges evaluated in sensitivity analyses).

SD: Standard deviation; ART: antiretroviral therapy; PMTCT: prevention of mother-to-child HIV transmission; AZT: azidothymidine (zidovudine); ARV: antiretroviral; NVP: nevirapine; ABC: abacavir; 3TC: lamivudine; LPV/r: lopinavir/ritonavir; TDF: tenofovir; FTC: emtricitabine; EFV: efavirenz; WHO: World Health Organizationa. Sensitivity and specificity were modeled with regard to true CD4 value of ≤350/μL (sensitivity: assay reports CD4 ≤350/μL when true CD4 is ≤350/μL; specificity: assay reports CD4 >350/μL when true CD4 is >350/μL). To be conservative with regard to the benefit of POC, we assumed in the base case that laboratory CD4 had 100% sensitivity and specificity to detect true CD4 ≤350/μL.b. In the base-case analysis, 13 weeks of antentatal AZT for non-ART eligible women are assumed in both strategies, based on median gestational age at booking in South Africa of 26 weeks. For ART-eligible women, 13 weeks of ART are assumed in the POC strategy and 3 weeks of AZT and 10 weeks of ART are assumed in the laboratory strategy.c. Please see S1 Table for description of assumptions of outpatient healthcare resource utilization.Selected model input parameters for the base-case analysis (See S1 Table for complete list and ranges evaluated in sensitivity analyses).