The proneural transcription factor ASCL1 regulates cell proliferation and primes for differentiation in neuroblastoma [ATAC-seq]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE202629
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To compare the function of endogenous ASCL1 in different neuroblastoma cell contexts, we have used CRISPR-mediated deletion to compare the effects of ASCL1 deletion in a MYCN-amplified and an ALK-driven neuroblastoma line and assessed the impact of ASCL1 knockout on chromatin accessiblity genome-wide using ATAC-seq ATAC-seq in parental and ASCL1 knockout lines
创建时间：
2022-11-30
