A proteomic view of basement membranes from human retinal blood vessels, inner limiting membranes, and lens capsules.

Data from ProteomeXchange, PXD ID: PXD001025. Experiment: ILM, file: ILM-2.mzml. Published as part of J Proteome Res. 2014 Jul 2 . From the Abstract: {{i}} Basement membranes (BMs) are extracellular matrix sheets comprising the laminins, type IV collagens, nidogens, and the heparan sulfate proteoglycans, perlecan, collagen XVIII and agrin. In intact BMs, BM proteins are physiologically insoluble and partially resistant to proteolytic digestion, making BMs a challenge to study. Here, three types of BMs from adult human eyes, the inner limiting membrane, the retinal vascular BMs and the lens capsule, were isolated for analysis by 1D-SDS-PAGE and LC-MS/MS ... {{/i}}