Expression data from human ovarian cancer cell line

LASS2 was used to identified as a novel suppressor in cancer development and progression. We explored roles of LASS2 in ovarian cancer invasion and metastasis. Lenti-LASS2 and Lenti-vector cells were constructed in 3AO cells through a lentiviral vector system. We preformed global gene expression analysis between Lenti-LASS2 and Lenti-vector cells in accordance with standard Aglient protocols to explore differentially expressed genes and signaling pathways involved by LASS2 overexpression. RNA was isolated from Lenti-vector and Lenti-LASS2 cells and hybridized on Agilent microarrays. The two groups were as follows: Lenti-LASS2 cells and Lenti-vector cells.