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Modeling sex differences in humans using isogenic induced pluripotent stem cells (RRBS). Modeling sex differences in humans using isogenic induced pluripotent stem cells (RRBS)

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA725204
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资源简介:
We developed a cellular model to study sex differences in humans. Using somatic cells from a mosaic Kleinefelter patient, we generated isogenic human induced pluripotent stem cell lines with different sex chromosome complements – 47,XXY / 46,XX / 46,XY and 45,X0. Overall design: Reduced representation bisulfite sequencing (RRBS) of six isogenic hiPSC cell lines - XX1, XX2, XX3, XY1, XY2, XY3
创建时间:
2021-04-26
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