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Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2p8s
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资源简介:
Human dipeptidyl peptidase IV/CD26 in complex with a cyclohexalamine inhibitor Descriptor: (1S,2R,5S)-5-[3-(TRIFLUOROMETHYL)-5,6-DIHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRAZIN-7(8H)-YL]-2-(2,4,5-TRIFLUOROPHENYL)CYCLOHEXANAMINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Scapin, G, Biftu, T. Deposit date: 2007-03-23 Release date: 2007-05-22 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Rational design of a novel, potent, and orally bioavailable cyclohexylamine DPP-4 inhibitor by application of molecular modeling and X-ray crystallography of sitagliptin Bioorg.Med.Chem.Lett., 17, 2007
创建时间:
2007-03-23
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