GRADE profile for the quality of evidence related to the assessment for Lumbar Spine using BMPs and ICBG.

1seven studies with a high risk of bias;
2Asymmetry in funnel plot;
3less than 75% of the studies present data that can be included in a meta-analysis;
4five studies with a high risk of bias;
5RR = 0.56;
6I2 = 79%;
7I2 = 77%;
8I2 = 70%;
9one study including more than 50% patients has a high risk of bias;
10I2 = 70%;
11only two studies including total 50 patients present data that can be included in a meta-analysis.