GRADE profile for the quality of evidence related to the assessment for Lumbar Spine using BMPs and ICBG.

1seven studies with a high risk of bias; 2Asymmetry in funnel plot; 3less than 75% of the studies present data that can be included in a meta-analysis; 4five studies with a high risk of bias; 5RR = 0.56; 6I2 = 79%; 7I2 = 77%; 8I2 = 70%; 9one study including more than 50% patients has a high risk of bias; 10I2 = 70%; 11only two studies including total 50 patients present data that can be included in a meta-analysis.