Summary of significant serum metabolites differentiating between ob/ob and B6 mice.

All the metabolites that have pt-test and VIP score >1 from OPLS-DA are shown for all, male, and/or female. The p values of the individual metabolic concentration in t-test are symbolized as *, **, and ***, indicating p0.05.aDirection of change is shown for obese mice compared to lean controls.bOther metabolites that do not belong to any of the metabolic categories listed above.cTotal number of significant metabolites with VIP score >1 and p