Clonal dynamics limits detection of selection in tumour xenograft CRISPR/Cas9 screens

These repository contains data and analysis code for the manuscript of the same name. This version has been updated for the accepted version of the paper. Details of individual files:<br>Lee_et_al__sample_details.tsv - details of samples present in counts file below; updated for accepted version of the paperLee_et_al__counts.tsv - gRNA counts from both pilot and larger screens described in paperLee_et_al__normalisation_factors.tsv - normalisation factors used in analysis of the above countsinvivo_gecko_lee_et_al_v2.zip - contains code and other files associated with the analyses of the above data; figures in the paper can be reproduced from these files; v2 is updated for the accepted version of the paper<br>Note: This repository does not contain the data or code for the simulation studies described in the paper, which is available upon reasonable request to the authors.