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AR transcriptional activity in response to kinase knockdown.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_AR_transcriptional_activity_in_response_to_kinase_knockdown_/289163
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Each of the six kinases was knocked down using two independent shRNAs in LNCaP and C42B cells. Cells were treated with varying levels of R1881 (0, 0.05 nM, 0.5 nM, 1 nM) for 2 or 24 hrs. Transcript levels of two AR target genes, TMPRSS2 and SGK, were measured by qPCR and compared to pLKO control and normalized to the housekeeping gene, PSMB6. Arrows represent statistically significant up or down regulation of mRNA levels.
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2015-12-02
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