MTAP Deficiency Sensitizes Pancreatic Cancer to Branched-Chain Amino Acid Transaminase inhibition by Enhancing the BCAT1 Mediated Metabolic Reprogramming
Somatic cells can be reprogrammed to pluripotent stem cells through the addition of just four transcription factors, OCT4, SOX2, KLF4 and c-MYC (OSKM). Although OSKM initiates reprogramming it is clea
In this study, we knockdown the expression of CTCF in EL4 cells by shRNA, followed by single cell RNA-seq on both wild type (WT) cells and CTCF-Knockdown (CTCF-KD) cells. Principal component analysis