Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor
收藏Protein Data Bank Japan2024-02-14 更新2026-03-21 收录
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https://pdbj.org/mine/summary/2fvd
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Cyclin Dependent Kinase 2 (CDK2) with diaminopyrimidine inhibitor Descriptor: (4-AMINO-2-{[1-(METHYLSULFONYL)PIPERIDIN-4-YL]AMINO}PYRIMIDIN-5-YL)(2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE, Cell division protein kinase 2 Authors: Crowther, R.L, Lukacs, C.M, Kammlott, R.U. Deposit date: 2006-01-30 Release date: 2006-10-10 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity. J.Med.Chem., 49, 2006
创建时间：
2006-01-30
