Post-OGTT excursions (AUC) of plasma identified and as-yet unidentified metabolitesa and serum insulin significantly changed by a weight loss and fitness intervention in adult women.

a metabolites measured by GC-TOF, AUC values are derived from quantion peak heights; unidentified metabolites indicated with their BinBase (BB) nomenclatures; values are mean ± SEM.b pre-diet and exercise intervention, n = 13.c post-diet and exercise intervention, n = 12.d p-value for a mixed effects linear model (no comparison met the 5% significance criteria after false discovery rate correction at a q = 0.05).AUC significantly different from zero; not shown are metabolite AUCs that were significantly different by intervention period but that were not different from zero at either time point due to high variance (see Results).