Detection of transcriptome changes caused by overexpression of NeuroD4 in U251 glioblastoma cells. Detection of transcriptome changes caused by overexpression of NeuroD4 in U251 glioblastoma cells

We demonstrated that overexpression of NeuroD4 can reprogram GBM cells into neuron-like cells. In order to further explore the mechanism of NeuroD4 causing this phenomenon, we performed mRNA sequencing on U251 cells infected with GFP and GFP+NeuroD4. Overall design: The mRNA changes of U251 cells infected with GFP and GFP+NeuroD4 were detected.