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Transcriptomic expression of A549 CDK2 KO cells treated or untreated with palbociclib

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE197600
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Inducing senescence in cancer cells is emerging as a new therapeutic strategy. We tested the senescence induction of palbociclib in CDK2 KO cells, and profiled these for senescence associated gene signatures. This was a CRISPR generated CDK2 KO clone in A549 cells. Transcriptomic analysis of A549 CDK2 KO cells treated with palbociclib and control. The experiment was performed in technical duplicates.
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2022-03-05
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