Ketamine evoked disruption of entorhinal and hippocampal spatial maps

<em>Companion code located at https://github.com/GiocomoLab/Masuda_et_al_2023</em> MEC_Neuropixels.zip <em>MEC spike times and behavior from acute Neuropixels insertions during a 1D VR linear track task</em> File names: [animal name]_[date]_baseline1_controlinjx1_ketamine1fr_corr.mat lickt = lick timestamps, of IR beam breaks lickx = position of animal at lick times post = timestamps of 50 Hz VR frames posx = position of animal at each VR frame speed = speed of animal at each VR frame trial = trial at each VR frame spike_depth: depth along electrode of peak channel of each cell all_cellCorrScore = correlation score between a trial and the baseline spatial template all_cellStabilityScore = spatial stability for each cell on each trial all_corrmatrix = firing correlation of each cell between each pair of trials all_drugEffectScores = [ketamine FR diff, control FR diff, ketamine FR effect score, ketamine corr effect score, spike depth] for each cell FR effect score = the ratio ketamine vs control of the differences between the avg FR of the pre-injection trials and the the avg FR of the equivalent number of trials post-injection corr effect score = difference between the average of the corrScore in the 25 trials before ketamine and the average of the corrScore in the 25 trials after ketamine appication all_fr = mean firing rate per cell per trial per spatial bin all_fr_smoothed = save as all_fr, smoothed with Gaussian kernel all_frTime = firing rate of each cell averaged over each VR frame all_peakiness = mean crest factor of each cell all_spatialinfo = mean spatial information of each cell all_spatialInfoCurve = spatial information of each cell on each trial all_spike_idx = spike times for each cell, in VR bins all_waveforms = waveforms of each cell avg_all_cellCorrScore = avarge cellCorrScores curves for each trial avg_all_corrmatrix = trial by trial correlation for all cells avg_all_fr: mean firing rate per position bin per trial over all cells avg_cell_fr: mean firing rate over full session per cell CA1_miniscope.zip <em>CA1 calcium transients from 1-photon imaging during a freely moving context exploration</em> Folder names: M[mouse number][F for female, nothing for male] behavIndividualsf.mat neuronIndivisualsf.mat sessions.mat thresh.mat