Gene expression changes in Corynebacterium glutamicum during iron limitation [Set I]

Iron is the fourth most abundant element in the Earth’s crust. However, the poor solubility of iron due to oxidation of ferrous iron to the almost insoluble ferric iron under aerobic conditions constitutes a considerable challenge for living organisms to obtain sufficient amounts of the iron available. In the present study, we set out to characterize the global gene expression of C. glutamicum under iron limitation in comparison to iron-replete conditions. C. glutamicum cells were cultured under iron deplete (1 µM) or replete (36 µM) conditions and were harvested at early exponential phase (OD600 4–5).