GenomePAM directs PAM characterization and engineering of CRISPR-Cas nucleases using mammalian genome repeats
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP582994
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资源简介：
We developed a method named GenomePAM that allows for direct PAM characterization in mammalian cells.Beyond PAM characterization, GenomePAM allows for simultaneous comparison of activities and fidelities among different Cas nucleases on thousands of match and mismatch sites across the genome using a single gRNA, and provides insight into the genome-wide chromatin accessibility profiles in different cell types.
创建时间：
2025-08-27
