The Commitment of the Human Cell Atlas to Humanity

The Human Cell Atlas (HCA) is a global partnership of scientists who are seeking to understand how the cells in our bodies work together to form our organs and carry out specific physiological functions essential to life. HCA scientists are creating a view of healthy cells and their behaviours in individuals, representing a diverse set of people to help better understand human biology, as well as the contributions of our environments and genetics to the ways in which our cells work to keep us well. Recognizing that many medical breakthroughs have not been beneficial to all because healthcare research has often been conducted without considering the impacts of variations in our genetic make-up, environmental exposures or life-experiences. Some previous scientific studies have been extractive and exploitative, failing to sufficiently consider the priorities of, or benefits to, contributing communities. In this narrative, HCA provides a set of principles and action items that have been adopted to affirm its commitment to promote equity so that the results of this global scientific endeavour are beneficial to all of humanity.

人类细胞图谱（HCA）是一项全球科学家的合作项目，旨在探究我们体内的细胞如何协同作用，形成器官并执行维持生命所必需的特定生理功能。HCA科学家正在构建一个健康细胞及其在个体中行为的视图，代表了一个多元化的群体，以更好地理解人类生物学，以及我们的环境暴露和遗传因素对我们细胞工作方式的影响。鉴于许多医学突破并未惠及所有人，因为医疗保健研究往往未考虑我们遗传构成、环境暴露或生活经历的差异性。一些先前的研究存在剥削性，未能充分考虑到贡献社区的优先事项或利益。在此叙述中，HCA提出了一系列原则和行动项目，以确认其致力于促进公平性的承诺，确保这一全球科学努力的结果能够惠及全人类。