Tissue-specific dysregulation of DNA methylation in aging
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Tissue-specific dysregulation of DNA methylation in aging
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2010-05-01
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Additional file 7: of Novel regional age-associated DNA methylation changes within human common disease-associated loci
BED file of combined 14 ageing studies. (BED 2508Â kb)
Figshare2016-12-14 更新90
Additional file 4: of Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1
Information about the different blood cell type deconvolution strategies that were benchmarked against the gold standard dataset (GSE77797). (XLSX 13 kb)
Figshare2024-02-12 更新30
Interindividual comparison of methylation profiling by MSAM
Interindividual variation in methylation profiling of human DNA samples were detected using two-tissue screening by MSAM. 0.5ug of DNA was serially digested with SmaI and XmaI followed by an adaptor l
NIAID Data Ecosystem30
A hyper-quiescent chromatin state is a barrier to productive regeneration during aging. [DNA-Seq]
Epigenetic alterations are one of the key hallmarks of aging. Emerging evidence in model organisms, senescent cell cultures and limitedly, murine, and human tissue samples suggest local effects impact
NIAID Data Ecosystem50
Exercise Mitigates Skeletal Muscle Epigenetic Aging. Exercise Mitigates Skeletal Muscle Epigenetic Aging
Exercise late in life mitigates skeletal muscle epigenetic aging, providing evidence that physical activity is a "fountain of youth". Overall design: TA muscle from 5 young sedentary mice, 5 24 month
NIAID Data Ecosystem30



