Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77
收藏Protein Data Bank Japan2024-07-03 更新2026-04-19 收录
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Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77 Descriptor: 3-(7-azanyl-1,8-naphthyridin-2-yl)-2-[(7-azanyl-1,8-naphthyridin-2-yl)methyl]-~{N}-(3-azanylpropyl)propanamide, CHLORIDE ION, RNA (5'-R(*GP*GP*CP*CP*CP*C)-3') Authors: Kiliszek, A, Ryczek, M, Blaszczyk, L. Deposit date: 2023-09-22 Release date: 2024-05-01 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Antisense RNA C9orf72 hexanucleotide repeat associated with amyotrophic lateral sclerosis and frontotemporal dementia forms a triplex-like structure and binds small synthetic ligand. Nucleic Acids Res., 52, 2024
创建时间:
2023-09-22



