首页/数据集/Mutational, transcriptional, and microRNA features in MLL translocated leukemia. Translocations in Acute Leukemia

Mutational, transcriptional, and microRNA features in MLL translocated leukemia. Translocations in Acute Leukemia

NIAID Data Ecosystem2026-03-09 收录

急性髓系白血病分子特征

MLL基因易位

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJEB9668 数据链接链接失效反馈

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资源简介：

We examined the mutational, transcriptional, and microRNA profiles in MLL translocated acute myeloid leukemia (AML).

应用场景：

创建时间：

2016-06-22

干细胞标记

急性髓系白血病分子特征

The leukemia stem cell (LSC) populations of acute myeloid leukemia (AML) exhibit phenotypic, genetic and functional heterogeneity that contribute to therapy failure and relapse. Progress towards under

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RUNX1/ETO and mutant KIT both contribute to programming the transcriptional and chromatin landscape in t(8;21) AML

急性髓系白血病分子特征

染色质与基因调控及基因组稳定性

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem80

Kasumi-1 AML1-ETO knockdown samples

急性髓系白血病分子特征

基因敲低表达谱分析

Kasumi-1 AML cells that were transfected in triplicate with AML1-ETO or luciferase siRNA constructs by either Amaxa nucleofection or Biorad siLentFect and incubated for 96 hours. Microarrays used to d

NIAID Data Ecosystem60

Zinc finger protein 521 overexpression is a feature of MLL-rearranged acute myeloid leukemia and contributes to the maintenance of myeloid differentiation block. Homo sapiens

急性髓系白血病分子特征

转录因子功能研究

ZNF521 is a multiple zinc finger transcription factor previously identified because abundantly and selectively expressed in normal CD34+ hematopoietic stem and progenitor cells. From microarray datase

NIAID Data Ecosystem110

Function of LPIN1 in human AML and hematopoiesis

急性髓系白血病分子特征

干细胞基因功能

LPIN1 was knocked down in human acute myeloid leukemia cell line OCI-AML3 and in human CD34+ umbilical cord blood cells after 48 hours of prestimulation using shRNA against human LPIN1 versus shRNA a

NIAID Data Ecosystem80

Mutational, transcriptional, and microRNA features in MLL translocated leukemia. Translocations in Acute Leukemia

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