Correlation analysis between AML cell sensitivity to the four study agents and BH3 profiling using multivariate mixed linear models of both p53 wild-type and p53 mutant cell lines.
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Coefficient β for Nutlin-3a, KPT-330 and Ara-C is positive when the increase of %apoptosis is related to larger %[BH3 peptide], and β for ABT-199 is negative when the decrease of %live cell number is related to larger %[BH3 peptide]. Correlation analysis between AML cell sensitivity to the four study agents and BH3 profiling using multivariate mixed linear models of both p53 wild-type and p53 mutant cell lines.
创建时间:
2015-09-16



