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Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methlation inhibitor guadecitabine

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NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE90681
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Comparison of gene expression in cisplatin resistant testicular germ cell tumor xenografts treated with vehicle (PBS) or the DNA methylation inhibitor guadecitabine Total RNA was isolated from flank xenograft tumors treated once per day for 4 days with 1.5 mg/kg guadecitabine or PBS. Drug was subcutaneous injection. Both control and guadecitabine treatments were in biological triplicates.
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2018-08-13
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