The biosynthesis of membrane lipids is an essential pathway for virtually all bacteria. Despite its potential importance for the development of novel antibiotics, little is known about the underlying

NIAID Data Ecosystem10

Crystal structure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex

酶结构解析

抗菌药物靶点

Crystal structure of the Pseudomonas aeruginosa MurG:UDP-GlcNAc substrate complex

NIAID Data Ecosystem10

Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+ppGpp-bound form, super-compressed

蛋白质结构解析

抗菌药物靶点

Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) ATP+ppGpp-bound form, super-compressed

NIAID Data Ecosystem10

G-quadruplex DNA as a target for pathogenic bacteria: efficacy of an extended naphthalene diimide ligand and mode of action

抗菌药物靶点

G-四链体功能

Guanidine DNA quadruplex (G4-DNA) structures convey a distinctive layer of epigenetic information that is critical for the regulation of key biological activities and processes as genome transcription

NIAID Data Ecosystem10

Structure of Kdac1-Citarinostat complex from Acinetobacter baumannii

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