Effect of Daunorubicin on T cell activation [RNA-Seq]

NIAID Data Ecosystem2026-05-02 收录

T细胞功能研究

药物作用机制

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https://www.ncbi.nlm.nih.gov/sra/SRP512426 数据链接链接失效反馈

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To determine the effect of DNR on T cell activation ,we treated T cells with DNR and analyzed their functions. Overall design: Comparative gene expression profiling analysis of RNA-seq for T cells after treated with DNR.

创建时间：

2025-06-30

Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes in Multiple Myeloma (MM) cell lines treated with DMSO and Indirubin-3’-monoxime (I3MO)

癌细胞转录组

药物作用机制

To determine what signaling pathways are affected by I3MO in MM cells, 5 MM cell lines including ANBL6, ANBL6 BR, ARP1, RPMI-8226, and U266, were cultured with DMSO or 5/10µM I3MO for 48 h. Total RNAs

NIAID Data Ecosystem60

RNA-seq of in vitro differeentiated Th subsets and IL-27+TGF-β-treated CD4+ T cells. RNA-seq of in vitro differeentiated Th subsets and IL-27+TGF-β-treated CD4+ T cells

免疫代谢

T细胞功能研究

IL-27 is an immunoregulatory cytokine whose essential function is to limit immune responses. We found that the gene encoding cholesterol 25-hydroxylase (Ch25h) was induced in CD4+ T cells by IL-27, en

NIAID Data Ecosystem40

WP2435 - Quercetin and Nf-kB / AP-1 induced apoptosis - Homo sapiens

细胞信号通路

药物作用机制

Quercetin is a flavonoid that is widely distributed in nature. In this pathway, its dual nature is depicted. On the one hand, it is capable of exerting anti-oxidant and anti-inflammatory effects by in

NIAID Data Ecosystem10

Inhibitory Effects of Vinpocetine on the Progression of Atherosclerosis Are Mediated by Akt/NF-κB Dependent Mechanisms in apoE -/- Mice

动脉粥样硬化治疗

药物作用机制

Background Recent studies have found additional roles for vinpocetine, a potent phosphodiesterase type I inhibitor, in anti-proliferation and anti-inflammation of vascular smooth muscle cells and canc

NIAID Data Ecosystem60

Momordicine I Suppresses Glioma Growth by Promoting Apoptosis and Impairing Mitochondrial Oxidative Phosphorylation. Momordicine I Suppresses Glioma Growth by Promoting Apoptosis and Impairing Mitochondrial Oxidative Phosphorylation

神经胶质瘤治疗

药物作用机制

RNA microarray was performed from glioma cell LN229 and GBM8401 that were treated with Momordicine (10 microM) for 48hr in comparison to DMSO vehicle control Overall design: To study the growth inhibi

NIAID Data Ecosystem30

Effect of Daunorubicin on T cell activation [RNA-Seq]

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