HIV-1 Protease WT (NL4-3) in Complex with PU2 (LR2-79)
收藏Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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HIV-1 Protease WT (NL4-3) in Complex with PU2 (LR2-79) Descriptor: Protease, SULFATE ION, diethyl ({4-[(2S,3R)-2-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl][(2S)-2-methylbutyl]amino}butyl]phenoxy}methyl)phosphonate Authors: Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. Deposit date: 2021-01-14 Release date: 2022-01-26 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.89 Å) Cite: HIV-1 Protease Inhibitors with a P1 Phosphonate Modification Maintain Potency against Drug Resistant Variants by Increased van der Waals Contacts with Flaps Residues To Be Published
创建时间：
2021-01-14
