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Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-23

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Protein Data Bank Japan2023-10-18 更新2026-03-28 收录
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Crystal Structure of the ER-alpha Ligand-binding Domain (L372S, L536S) in complex with DMERI-23 Descriptor: (2E)-3-(4-{[(1S,2R,4S,5S,6S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]heptane-2-sulfonyl](2,2,2-trifluoroethyl)amino}phenyl)prop-2-enoic acid, Estrogen receptor Authors: Min, J, Nwachukwu, J.C, Min, C.K, Njeri, J.W, Srinivasan, S, Rangarajan, E.S, Nettles, C.C, Yan, S, Houtman, R, Griffin, P.R, Izard, T, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Nettles, K.W. Deposit date: 2021-08-10 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Dual-mechanism estrogen receptor inhibitors. Proc.Natl.Acad.Sci.USA, 118, 2021
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2021-08-10
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