The crystal structure of EGFR T790M/C797S with the inhibitor HCD2892
收藏Protein Data Bank Japan2023-11-29 更新2026-04-25 收录
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The crystal structure of EGFR T790M/C797S with the inhibitor HCD2892 Descriptor: 5-chloranyl-N-[5-chloranyl-2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-(1-ethylsulfonylindol-3-yl)pyrimidin-2-amine, Epidermal growth factor receptor Authors: Zhu, S.J. Deposit date: 2021-10-22 Release date: 2022-06-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.507 Å) Cite: Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022
创建时间：
2021-10-22
