Figure 5

Figure 5 and Figure 5I PDFs: Uncropped blots used in final figures. Figure 5A-J file: Sheet 1 (b): Western blot densitometric quantification for membrane bound APP. Total APP, and protein levels of C-terminal fragments (α and β) raw densitometry and quantification of protein levels relative to full length APP, presented as percentage of total full-length APP [Signal intensity of the α or β fragment/signal intensity of full-length APP] × 100). Sheet 2 (d): raw densitometry values for BACE1 in cortical tissue from 3-5-month old 5xFAD and TgA-5xFAD mice. Sheet 3 (f): Raw densitometric quantification of protein levels of Aβ-degrading enzyme, matrix-metalloproteinase-2 (MMP-2). Sheet 4 (h): Raw densitometry and quantification for Aβ-degrading enzyme neprilysin. Sheet 5 (j): Raw analyses for Aβ-degrading enzyme, Insulin-degrading enzyme (IDE).