Improved split TEV GPCR beta-arrestin recruitment assays
收藏doi.org2025-03-23 收录
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http://doi.org/10.17632/fd45dm2bz5.1
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资源简介：
Data set for "Improved split TEV GPCR beta-arrestin recruitment assays via systematic analysis of signal peptide and a beta-arrestin binding motif variants" as published in Wu et al., Biosensors 2023, 13(1), 48; https://doi.org/10.3390/bios13010048
Data contain firefly luciferase readings from split TEV GPCR beta-arrestin-2 recruitment assays in four cell lines (HEK-293, U-2 OS, HeLa, and PC12-tetOff cells).
Data from dose response assays for GLP1R and GCGR were performed in HEK-293 cells (data files "DRC").
本数据集源自于Wu等人在2023年发表在《生物传感器》杂志上的论文《通过系统分析信号肽和β-arrestin结合基序变体，改进TEV GPCR β-arrestin募集检测方法的分割TEV GPCR β-arrestin-2募集检测数据集》（原文：Data set for "Improved split TEV GPCR beta-arrestin recruitment assays via systematic analysis of signal peptide and a beta-arrestin binding motif variants" as published in Wu et al., Biosensors 2023, 13(1), 48; https://doi.org/10.3390/bios13010048）。数据集包含来自四株细胞系（HEK-293、U-2 OS、HeLa和PC12-tetOff细胞）分割TEV GPCR β-arrestin-2募集检测的萤火虫荧光素酶读数。针对GLP1R和GCGR的剂量响应实验数据亦在HEK-293细胞中进行，相关数据文件命名为“DRC”。
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