Resting State MRI data from healthy control (HC), Parkinson's disease with normal cognition (PD-NC), and Parkinson's disease with mild cognitive impairment (PD-MCI) cohorts

## Dataset Description
This dataset is part of a longitudinal study investigating **Parkinson's Disease (PD)** and its associated cognitive impairments. Resting-state fMRI data were collected from participants, including healthy controls (HC) and Parkinson's Disease patients with normal cognition (PD-NC) or mild cognitive impairment (PD-MCI). The dataset is organized following the **Brain Imaging Data Structure (BIDS)** specifications.

### License
This dataset is shared under the [CC0 1.0 Universal (CC0 1.0) Public Domain Dedication](https://creativecommons.org/publicdomain/zero/1.0/). Please acknowledge this dataset in publications by citing it appropriately.

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## Study Information
- **Title**: Resting State MRI data from healthy control (HC), Parkinson's disease with normal cognition (PD-NC), and Parkinson's disease with mild cognitive impairment (PD-MCI) cohorts
- **Principal Investigator**: James E. Galvin
- **Ethics Approval**: This study was approved by the Institutional Review Board (IRB) at New York University (NYU). All participants provided informed consent.

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## Data Acquisition
### MRI Details
- **Scanner Manufacturer**: Siemens
- **Model**: TrioTim
- **Magnetic Field Strength**: 3 Tesla
- **Sequence**: Echo Planar Imaging (EPI)
- **Repetition Time (TR)**: 2000 ms
- **Echo Time (TE)**: 29 ms
- **Flip Angle**: 90°
- **Slice Thickness**: 3.5 mm
- **Spacing Between Slices**: 3.5 mm

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## Dataset Structure
The dataset contains the following main directories and files:

- **`/participants.json`**: Contains metadata describing participant demographics and group information.
- **`/sub-<label>/`**: Subdirectories for each participant containing:
- `anat/`: Anatomical MRI data (T1-weighted images).
- `func/`: Functional MRI data (resting-state).

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## Key Files
### `participants.tsv`
A tab-separated file containing participant demographics, group, and other relevant information.

| participant_id | group | age | sex |
|----------------|---------|-----|------|
| sub-MJF001 | PD-MCI | 68 | M |
| sub-MJF008 | HC | 61 | F |

### `task-rest_bold.json`
Metadata file describing the resting-state functional MRI task. Key fields include:
- **TaskName**: "rest"
- **Modality**: "MR"
- **TR**: 2000 ms
- **EchoTime**: 29 ms

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## Usage Notes
- Please refer to the associated publication for detailed study design and analysis pipelines.

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## Acknowledgments
We acknowledge the contributions of all study participants and research team members. Special thanks to the Micheal J. Fox Foundation for supporting this research.

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