Multiplexed isobaric quantitative cross-linking reveals drug-induced interactome changes in breast cancer cells
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https://www.omicsdi.org/dataset/pride/PXD029350
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资源简介:
In vivo application of an extended set of six iqPIR reagents (6-plex iqPIR) allowing multiplexed quantitative interactome analysis of up to six biological samples in a single LC-MS acquisition. Multiplexed iqPIR is demonstrated on MCF-7 breast cancer cells treated with five different Hsp90 inhibitors revealing large scale protein conformational and interaction changes specific to the molecular class of the inhibitors.
创建时间:
2023-03-11



