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Temperature-Controlled Synthesis of Substituted Pyridine Derivatives via the [5C + 1N] Annulation of 1,1-Bisalkylthio-1,4-pentanedienes and Ammonium Acetate

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A novel temperature-controlled one-pot synthesis of substituted pyridine derivatives via [5C + 1N] annulation of 1,1-bisalkylthio-1,4-pentanedienes and ammonium acetate is developed, and possible mechanisms leading to the divergent formation of the two types of pyridines are discussed.

创建时间:
2016-06-03
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