Quality of 69 genotyped mutations in MC4R in UK Biobank participants of European ancestry.

The sequencing dataset is based on the European subset only because of allele frequency differences for some variants between the European and other populations, such as the African American population. It is also based on the same subset that was analyzed in our analyses of the genotyping data. *Refers to the number of individuals who were carriers in the genotyped dataset but noncarriers in the sequencing dataset. **Refers to the number of individuals who were carriers in the sequenced dataset but noncarriers in the genotyping dataset. *** FFP = high (>25%) false positive proportion; NFP = high (>25%) false negative proportion. MC4R, melanocortin 4 receptor gene. (XLSX)