Human ES cells reveal recurrent genomic instability at 20q11.21
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Human ES cells reveal recurrent genomic instability at 20q11.21
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2010-05-16
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Supplementary Material for: One-step leaping evolution from an autosomal pair to the heteromorphic sex chromosomes
Background: Sex chromosomes evolve from an autosomal pair after the acquisition of a sex-determining gene. The primary sex chromosomes are homomorphic in both sexes and often undergo heteromorphism in
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Summary of Integrated mESC Genomic Data.
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Chromothripsis in healthy individuals affects multiple protein-coding genes and can result in severe congenital abnormalities in offspring.
This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series
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Identification of recurrent chromosome breaks underlying structural rearrangements in mammary cancer cell lines [DNA-seq]. Identification of recurrent chromosome breaks underlying structural rearrangements in mammary cancer cell lines [DNA-seq]
Cancer genomes are characterized by accumulation of small-scale somatic mutations as well as large-scale chromosomal deletions, amplifications, and complex structural rearrangements. This characterist
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