Structure of beta-secretase complexed with inhibitor
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Structure of beta-secretase complexed with inhibitor Descriptor: Beta-secretase 1, L-PROLINAMIDE, N-[(2S)-1-({(2S,3R)-3-hydroxy-1-[(2-methylpropyl)amino]-1-oxobutan-2-yl}amino)-3-phenylpropan-2-yl]-5-[methyl(methylsulfonyl)amino]-N'-[(1R)-1-phenylethyl]benzene-1,3-dicarboxamide Authors: Ghosh, A, Tang, J, Venkateswara, R.K, Yadav, N, Anderson, D, Gavande, N, Huang, X, Terzyan, S. Deposit date: 2012-08-08 Release date: 2012-10-10 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure-based design of highly selective beta-secretase inhibitors: synthesis, biological evaluation, and protein-ligand X-ray crystal structure. J.Med.Chem., 55, 2012
创建时间：
2012-08-08
