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Distinct oligomeric assemblies of STING induced by non-nucleotide agonists

Figshare2025-04-11 更新2026-04-28 收录

数据链接：

https://figshare.com/articles/dataset/Distinct_oligomeric_assemblies_of_STING_induced_by_non-nucleotide_agonists/26528224 数据链接链接失效反馈

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资源简介：

These are PDB and MRC files for the structures described in our manuscript.

应用场景：

创建时间：

2025-04-11

STING蛋白

抗肿瘤药物开发

STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 4 Descriptor: 4-{5-[(1Z)-3-{[2-(3-carboxypropanoyl)-6-methoxy-1-benzothiophen-5-yl]oxy}prop-1-en-1-yl]-6-methoxy-1-benzothiophen

Protein Data Bank Japan2023-10-11 更新70

Human Stimulator of Interferon Genes

STING蛋白

干扰素信号通路

Human Stimulator of Interferon Genes Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine

Protein Data Bank Japan2023-10-04 更新20

Cryo-EM structure of full-length chicken STING in the cGAMP-bound dimeric state

STING蛋白

免疫应答机制

Cryo-EM structure of full-length chicken STING in the cGAMP-bound dimeric state Descriptor: Stimulator of interferon genes protein, cGAMP Authors: Shang, G, Zhang, C, Chen, Z.J, Bai, X, Zhang, X. Depo

Protein Data Bank Japan2024-03-20 更新20

Human wtSTING in complex with 2',2'-difluoro-3',3'-c-di-GMP

STING蛋白

X射线晶体学

Human wtSTING in complex with 2',2'-difluoro-3',3'-c-di-GMP Descriptor: 2-azanyl-9-[(1~{R},6~{R},8~{R},9~{R},10~{R},15~{R},17~{R},18~{R})-17-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-9,18-bis(fluora

Protein Data Bank Japan2024-01-24 更新20

STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 11

STING蛋白

抗肿瘤药物开发

STING C-terminal Domain Complexed with Non-cyclic Dinucleotide Compound 11 Descriptor: 4,4'-{propane-1,3-diylbis[oxy(5-methoxy-1-benzothiene-6,2-diyl)]}bis(4-oxobutanoic acid), fusion protein of Ubiqu

Protein Data Bank Japan2023-10-11 更新20

Distinct oligomeric assemblies of STING induced by non-nucleotide agonists

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